Author/Authors :
Hamedi ، J نويسنده Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran Hamedi , J , Mohammadipanah، F نويسنده Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran Mohammadipanah, F , Amoozegar، MA نويسنده Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran Amoozegar, MA , Dehghan، S نويسنده Microbial Biotechnology laboratory, Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran Dehghan, S
Abstract :
In a screening program for antibiotic producer rare-actinobacteria from soil of Iran, a novel moderately halophilic actinobacter (Q70) was isolated. The strain had the ability of antibiotic production against methicillin resistant Staphylococcus aureus. Maximum antibiotic production was obtained in the medium containing 10% (w/v) NaCl. The strain Q70 had also activity against Enterococcus faecalis, Bacillus subtilis and Pseudomonas aeruginosa. The antibiotic extracted from fermentation broth had low toxicity (681/3 ?g/ml LC50) against Artemia salina in brine shrimp lethality test. The antibiotic produced by strain Q70 had polar structure. The strain Q70 is proposed as a new species with the name of Nocardiopsis iraniensis with considering the significant morphological, physiological, molecular and chemotaxonomical differences between Q70 and other species of Nocardiopsis.
