Author/Authors :
Rajabalinia، Hasan نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Ghobakhlou، Mehdi نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Nikpour، Shahriar نويسنده Loghman Hakim Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Dabiri، Reza نويسنده hani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Bahriny، Rasoul نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Jahani Sherafat، Somayeh نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , ketabi Moghaddam، Pardis نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Mohammadalizadeh، Amirhoushang نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences ,
Abstract :
Aim: The purpose of the present study was to evaluate the number and proportion of various causes of upper
gastrointestinal bleeding and actual numbers of non-NSAID, non-Helicobacter pylori (H.pylori) peptic ulcers seen in
endoscopy of these patients.
Background: The number and the proportion of patients with non- H.pylori, non-NSAIDs peptic ulcer disease leading
to upper gastrointestinal bleeding is believed to be increasing after eradication therapy for H.pylori.
Patients and methods: Medical records of patients referred to the emergency room of Taleghani hospital from 2010
with a clinical diagnosis of upper gastrointestinal bleeding (hematemesis, coffee ground vomiting and melena) were
included in this study. Patients with hematochezia with evidence of a source of bleeding from upper gastrointestinal tract
in endoscopy were also included in this study.
Results: In this study, peptic ulcer disease (all kinds of ulcers) was seen in 61 patients which were about 44.85% of
abnormalities seen on endoscopy of patients. Among these 61 ulcers, 44 were duodenal ulcer, 22 gastric ulcer (5 patients
had the both duodenal and gastric ulcers). Multiple biopsies were taken and be sent to laboratory for Rapid Urease Test
and pathological examination. About 65.53% of patients had ulcers associated with H.pylori, 9.83% had peptic ulcer
disease associated with NSAIDs and 11.47% of patients had ulcers associated with both H.pylori and consumption of
NSAIDs. 13.11% of patients had non-NSAIDs non- H.pylori peptic ulcer disease.
Conclusion: The results of this study supports the results of other studies that suggest the incidence of H.pylori infection
related with duodenal ulcer is common, and that non-H pylori and non-NSAIDs duodenal ulcer is also common.
