Author/Authors :
Rajabalinia، Hassan نويسنده Gastroenterology and Liver diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran , , Dabiri، Reza نويسنده hani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Shahbazi، Shahin نويسنده Gastroenterology and Liver diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran , , Ghobakhlou، Mehdi نويسنده Taleghani Hospital, Internal Medicine Department, Shahid Beheshti University of Medical Sciences , , Bahreiny، Rasoul نويسنده Gastroenterology and Liver diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran , , Molaei، Mahsa نويسنده , , Rostami Nejad، Mohammad نويسنده Gastroenterology and Liver Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran , , Fatemi Tabatabaei، Seyed Reza نويسنده Department of Physiology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahwaz, Ahwaz, Iran ,
Abstract :
Coeliac disease (CD) is an autoimmune disorder which leads to chronic inflammation of the gut. Untreated CD is
associated with upper gastrointestinal malignancies, Small-bowel lymphoma and adenocarcinoma are recognized
complications of untreated coeliac disease (CD). We report the case of a 43-year-old male suffering from CD who was
treated with a gluten-free diet one year, presenting with complaints of intractable nausea and vomiting. After several
studies, He underwent push enteroscopy, which identified one large mass lesion in the third part of duodenum. However,
histopathological examination showed adenocarcinoma. Subsequently, a duodenal segment resection was performed.
After surgery, the patient recovered well and left our hospital in good condition. Clinicians should take into small bowel
adenocarcinoma is rare but associated with CD particularly in CD patients with worrying symptoms such as nausea and
vomiting unresponsiveness to treatment and these patients should be screened for long term complications like
malignancy.