Author/Authors :
Yazdani، Mohammad Reza نويسنده Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan , , Kassaian، Nazila نويسنده Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan , , Ataei، Behrooz نويسنده Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan , , Nokhodian، Zary نويسنده Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan , , Adibi، Peyman نويسنده ,
Abstract :
Objectives: Patients with hereditary bleeding disorders are at risk of
viral infection such as hepatitis C due to frequent transfusion of blood
and blood products. This study aimed to determine the prevalence of
hepatitis C and associated risk factors in hemophilic patients in Isfahan,
the second big province in Iran.
Methods: In a descriptive study, patients with hemophilia in Isfahan
province were enrolled. A questionnaire, including demographic and
risk factors of hepatitis C was completed through a structured interview
with closed questions by a trained interviewer for each patient and
HCV-Ab test results were extracted from patient records.
Results: In this study, 232 of 350 patients with hemophilia A and B
(66%) were positive for hepatitis C. Based on Multivariate Logistic
Regression model, no independent risk factor was found.
Conclusions: Prevalence of hepatitis C in patients with haemophilia A
and B in Isfahan is high. Since no independent risk factor for hepatitis
C disease was found in this high risk group, it can be concluded that
multitransfusion is the only predictor for hepatitis C.
