Author/Authors :
Avijgan، Majid نويسنده MD, Department of Infectious and Tropical Diseases, Isfahan University of Medical Sciences, Isfahan , , Meidani، Mohsen نويسنده Department of Infectious Diseases, Isfahan University of Medical Sciences, Isfahan , , Salesi، Mansour نويسنده MD, Department of Rheumatology, Isfahan University of Medical Sciences, Isfahan , , Rezaei، Farshid نويسنده MD, Department of Infectious and Tropical Diseases, Isfahan University of Medical Sciences, Isfahan ,
Abstract :
Systemic lupus erythematosus (SLE) is a chronic inflammatory
disease of unknown cause. In this study, we report a case of SLE
that was presented with persistent vomiting and liver involvement.
To our knowledge, this is the first description of a patient
with hepatic necrosis as the initial presentation of SLE in a previously
healthy woman without any significant past medical
history. In the literature, we found few cases of SLE with liver
necrosis. In addition, all the cases found had a past medical history
of a missed abortion or other complications of the disease.
Therefore, if a young woman presents hepatic necrosis with a
background of a previously missed abortion, it is better to perform
anti-nuclear antibody (ANA) and anticardiolipin antibody
tests as a preventive method for early diagnosis and early treatment.