Author/Authors :
Ghayour-Mobarhan، Majid نويسنده MD, PhD, Cardiovascular Research Center, Avicenna (Bu-Ali) Research Institute, Mashhad University of Medical Science, Mashhad , , Kazemi-Bajestani، Seyyed Mohammad Reza نويسنده MSc, Radboud University Nijmegen Medical Center, Nijmegen , , Ferns، Gordon نويسنده PhD, Institute for Science and Technology in Medicine, University of Keele, Stoke on Trent, Staffordshire, ST4 7QB ,
Abstract :
Objectives: Lipid Clinics are specialized centers for clinical assessment
and follow up of patients with dyslipidaemia in order to
deliver an acceptable improvement in their lipid profiles. We assessed
the changes in lipid profile of dyslipidemic patients attending
a Lipid Clinic over a 1 year period on lipid-lowering therapy.
Methods: Dyslipidemic patients (n=238) were recruited from the
Lipid Clinic at the Royal Surrey County Hospital, Guildford,
UK. All patients were regularly seen at the clinic and the compliance
of lipid-lowering drug consumption, prescribed by the consultant
was assessed over a period of one year.
Results: The mean age of the patients was 55.2 ± 0.86 years and
the male/female ratio was 143/95. The lipid profiles of patients
attending the Lipid Clinic over the period of one year of close
monitoring changed significantly. Triglyceride, total cholesterol
and low density lipoprotein cholesterol were reduced by 27.04%,
20.48% and 22.67%, respectively (P < 0.001) and high density lipoprotein
cholesterol rose by 8.96% (P < 0.001); the 10-year calculated
coronary risk factor of all patients decreased significantly
(39.29%, P < 0.001).
Conclusions: Our findings confirmed the effectiveness of a Lipid
Clinic in the management of lipid profile and cardiovascular risk
of dyslipidemic patients.