Author/Authors :
Ghazanfari، Zahra نويسنده MSc, Kerman University of Medical Science, Physiology Research Centre, Jahad street, Kerman , , Haghdoost، Ali-Akbar نويسنده , , Alizadeh، Sakineh Mohammad نويسنده MSc, Kerman University of Medical Science, Physiology Research Centre, Jahad street, Kerman , , Atapour، Jamileh نويسنده MD,PhD,Kerman University of Medical Science, Faculty of Health, Haftbagh-Alavi Highway, Kerman , , Zolala، Farzaneh نويسنده Regional Knowledge Hub for HIV/ AIDS Surveillance, Biostatistics and Epidemiology Department, Kerman University of Medical Sciences ,
Abstract :
Objectives: Early diagnosis of diabetes is crucially important in
reduction of the complications. Although HbA1c is an accurate
marker for the prediction of complications, less information is
available about its accuracy in diagnosis of diabetes. In this study,
the association between HbA1c and FBS was assessed through a
cross-sectional population-based study.
Methods: A random sample of population in Kerman city was
selected. The total number was 604 people. Their HbA1c and fasting
blood sugar (FBS) were tested. The association between
HbA1c and FBS and also their sensitivity, specificity and predictive
values in detection of abnormal values of each other were
determined.
Results: The association of HbA1c with FBS was relatively strong
particularly in diabetic subjects. Generally, FBS was a more accurate
predictor for HbA1c compared with HbA1c as a predictor of FBS.
Although the optimum cutoff point of HbA1c was > 6.15%, its precision
was comparable with the conventional cutoff point of > 6%.
Conclusions: In conclusion, FBS sounds more reliable to separate
diabetic from non-diabetic subjects than HbA1c. In case of being
interested in using HbA1c in screening, the conventional cutoff
points of 6% is an acceptable threshold for discrimination of diabetics
from non-diabetics.
