Author/Authors :
Shaabanis، Ahmad نويسنده Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, P.O. Box 19396-4716 Tehran, I.R. IRAN , , Ghadari,، Rahim نويسنده Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, P.O. Box 19396-4716 Tehran, I.R. IRAN , , Rezayan، Ali Hossein نويسنده Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, P.O. Box 19396-4716 Tehran, I.R. IRAN ,
Abstract :
The synthesis of functionalized 2-oxo-2H-coumarin derivatives has been studied by a one-pot reaction of o-hydroxybenzaldehyde, ethyl 2-bromoacetate and triphenylphosphine in the presence of catalytic amount of triethyl amine in EtOAc, water or under solvent free conditions. We have found the best results obtained under solvent free condition.