Author/Authors :
Chen، Xiao-Jun نويسنده Department of Reproductive Endocrinology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China , , Wu، Li-Ping نويسنده Department of Reproductive Endocrinology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China , , Lan، Hai-Lian نويسنده Department of Reproductive Endocrinology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China , , Zhang، Li نويسنده , , Zhu، Yimin نويسنده ,
Abstract :
Background: The aim of this study was to investigate whether several clinical variables can affect
the pregnancy rate of intracervical insemination (ICI) using cryopreserved donor spermatozoa.
Materials and Methods: In this retrospective study, age, years of infertility, cervicitis, urinary
luteinizing hormone (LH) surge, insemination number, uterus position, endometrial thickness and
morphology, maximal follicle diameter, and the number of dominant follicles on the day of human
chorionic gonadotropin (HCG) administration were retrospectively analyzed in 501 women who
underwent their first ICI cycle using cryopreserved donor spermatozoa.
Results: Increased age, length of infertility ( > 5 years), retroverted uterine position, and endometrial
thickness ( < 7 mm or > 14 mm) were associated with lower rates of pregnancy.
Conclusion: In older women with infertile periods longer than five years, especially those with a
retroverted uterus, intrauterine insemination (IUI) combined with ovarian stimulation should be
recommended. In vitro fertilization with donor spermatozoa (IVFD) should be offered earlier to
achieve a much higher success rate.
