ACUTE REFRACTORY INFLAMMATORY BOWEL DISEASE AND CYCLOSPORIN

During the period May 1995 to March, 1997, we treated 08 patients (03 female, 05 male: 06 with Crohnʹs disease and 02 with ulcerative colitis) with sever inflammatory bowel disease as per Truelove and Wittʹs criteria with Cyclosporin as a measure to avoid surgery after failure of conventional therapy, i.e. intravenous steroids, 5-aminosalicylate and elemental diet supplemented with parenteral nutrition. Six patients responded completely while two patients showed partial response and had to have proctocolectomy within three months.