Missed Abortion and Application of Misoprostol

Background: Spontaneous abortion is categorized as threatened, inevitable, incomplete, complete, or missed. Abortion can be further categorized as sporadic or recurrent. By definition, a missed abor¬tion is an in utero death of the embryo or fetus before the 20th week of gestation with retained conception products. Missed abortions may also be referred to as blighted ovum or an anembryonic pregnancy. Materials and methods: A prospective-pathological analysis of 100 missed abortion pregnancies that were diagnosed and treated at the obstetrics- gynecology clinic in Pristina were included. Patients were analyzed based on age, parity, gestational age, method of misoprostol application, effective duration from the moment of application to abortion, and adverse effects from applying misoprostol. Results: In 25 (25%) pregnancies (15 at the end of week 10 pregnant Vlll and IX of the week until the end of the week XII) one tablet of misoprostol was applied to the rear vaginal fornix for 3 h, and the effect was achieved in a mean of 10 h for the first group, while it was achieved in 11 h in the second group. Thus, the average efficiency was 10.5 h. After applying three tablets of misoprostol to the rear vaginal fornix, 11 abortions occurred (44%), with the use of four tablets seven (28%) aborted, and with five tablets three (12%) aborted. There was average bleeding in 60 (67.41%) aborted pregnancies, and bleeding of the package in 15 (16.85%). Conclusion: Administra¬tion of misoprostol to women with a missed abortion produced spontaneous expulsion and reduced the need for surgical treatment.