Proline-catalysed asymmetric amination of ,(alpha)-(alpha)disubstituted aldehydes: synthesis of configurationally stable enantioenriched (alpha)-aminoaldehydes

Proline-catalysed amination of (alpha),(alpha)-disubstituted racemic aldehydes with azodicarboxylates proceeds smoothly to give configurationally stable scalemic aldehydes and oxazolidinones in up to 86% ee.