Title of article
Organocatalytic asymmetric (alpha)-bromination of aldehydes and ketones
Author/Authors
Bertelsen، S?ren نويسنده , , Halland، Nis نويسنده , , Bachmann، Stephan نويسنده , , Marigo، Mauro نويسنده , , Braunton، Alan نويسنده , , J?rgensen، Karl Anker نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-4820
From page
4821
To page
0
Abstract
The first organocatalytic enantioselective (alpha)-bromination of aldehydes and ketones is presented; a C2-symmetric diphenylpyrrolidine catalyst afforded the (alpha)-brominated aldehydes in good yields and up to 96% ee, while ketones were (alpha)-brominated by a C2-symmetric imidazolidine in up to 94% ee; furthermore, the organocatalytic enantioselective (alpha)-iodination of aldehydes is also demonstrated to proceed with up to 89% ee.
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Serial Year
2005
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Record number
68630
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