What These Trends Suggest?

Problem statement: Global warming is one of most significant factors affecting the biological evolution and the influenza is the disease that threatens humans with possible epidemics or pandemics. It would be important to understand if the global warming would have potential impact on the evolution of influenza virus. For this aim, the first would be to study the trend of evolution of proteins from influenza A virus and compare it with the trend in global warming. Approach: The evolution of polymerase acidic proteins of influenza A virus from 1918-2008 was defined using the unpredictable portion of amino-acid pair predictability. Then the trend in this evolution was compared with the trend in the global temperature, the temperature in north and south hemispheres and the temperature in influenza A virus sampling site and species carrying influenza A virus. Results: The similar trend was found between global warming and evolution of polymerase acidic proteins although we could not correlate them at this stage of study. Conclusion: The study suggested the potential impact of global warming on the evolution of proteins from influenza A virus.