• Title of article

    5-Hydroxyuracil can form stable base pairs with all four bases in a DNA duplex

  • Author/Authors

    Thiviyanathan، Varatharasa نويسنده , , Somasunderam، Anoma نويسنده , , Volk، David E. نويسنده , , Gorenstein، David G. نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -3
  • From page
    4
  • To page
    0
  • Abstract
    NMR studies, UV-monitored melting experiments, and ab initio calculations show that 5-hydroxyuracil, produced by the oxidative de-amination of cytosines by reactive oxygen species, can form stable base-pairs with dA, dG, dC and dT residues in a DNA duplex, providing a basis for the in-vivo incorporation of 5-hydroxyuracil during DNA replication.
  • Keywords
    Abamectin compatibility , Liriomyza trifolii , Biological control , DIGLYPHUS ISAEA , Greenhouse , IPM
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Serial Year
    2005
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Record number

    68908