Title of article
Facilitation of addition–elimination reactions in pyrimidines and purines using trifluoroacetic acid in trifluoroethanol
Author/Authors
Henderson، Andrew J. نويسنده , , Golding، Bernard T. نويسنده , , Whitfield، Hayley J. نويسنده , , Griffin، Roger J. نويسنده , , Hardcastle، Ian R. نويسنده , , Meneyrol، Jerome نويسنده , , Mesguiche، Veronique نويسنده , , Sayle، Kerry L. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
-2801
From page
2802
To page
0
Abstract
SNAr displacement reactions of 6-cyclohexylmethoxy-2-fluoropurine, 6-amino-2butylsulfonyl-4-cyclohexylmethoxypyrimidine and 2-amino-6-chloropurine with substituted anilines (e.g. the weakly nucleophilic 4-aminobenzenesulfonamide) are dramatically accelerated in the presence of trifluoroacetic acid and occur especially efficiently in 2,2,2-trifluoroethanol solvent
Keywords
starburstinfrared , evolution galaxies
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Serial Year
2003
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Record number
69014
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