The Effect of Indian Liquorice on Fertility Potentials of Male Rat

The use of herb as an adjutant form of medical treatment is gaining popularity all over the world. This study is aimed at determining the of Indian liquoricice on fertility potentials of male wister rats. A total of fifty five rats divided into seven groups were used in this study. A varying dose of 200 and 400mg/kg of the extract were used. Parameters used in the methodology were weight of testis, malonildiahidehyde concentration, histological study, hormonal assay and sperm analysis. Results revealed a significant change in weight of testes, inhibition of testicular tissue peroxidation, testosterone levels, parameters of sperm analysis such as sperm concentration and motility in comparison to the negative control. Obvious cellular changes were also observed in the liquorice treated groups. These changes were brought back to almost near pre-treatment values in the reversal groups. The changes observed in groups co- treated with vitamin E were minimal and statistically insignificant. The results suggest that the seed extract of Indian liquorice has a negative effect on the fertility potentials of the male rats and also shows oxidative properties.