Facile ultrasound promoted one-pot synthesis of polyhydroquinoline derivatives using RuCl3

A facile and convenient protocol was developed for the four component coupling of aldehydes, dimedone, ethyl acetoacetate and ammonium acetate to form polyhydroquinoline derivatives in the presence of RuCl3 under ultrasound irradiation in good to high yields (70-94%) and short reaction times (5-20 min).