Author/Authors :
Manjunatha ، Jamballi G. نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India , , Kumara Swamy، Bahaddurghatta E. نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Shimoga, Karnataka 577451, India , , Mamatha ، Ganjeenahalli P. نويسنده Department of Pharmaceutical Chemistry, Kadur, Kuvempu University, Karnataka, India , , Gilbert، Ongera نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India , , Sherigara ، Bailure Sherigara S. نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Karnataka, India ,
Abstract :
A voltammetric method using a poly(maleic acid) modified carbon paste
electrode was developed for the quantification of dopamine. The modified electrode
exhibited stable and sensitive current responses towards dopamine and potassium
ferrocyanide. Compared with a bare CPE, the modified electrode exhibits a remarkable
shift of the oxidation potentials of dopamine in the cathodic direction and a drastic
enhancement of the anodic current response. The separation between anodic and cathodic
peak potentials for dopamine is 0.84 V in 0.2 M phosphate buffer solution (PBS) at pH 7.0
at modified carbon paste electrodes. The poly (maleic acid) CPE was also effective to
simultaneously determine dopamine and uric acid in a mixture and resolved the
overlapping anodic peaks of these two species into two well-defined voltammetric peaks
in cyclic voltammetry. The proposed method showed excellent stability and
reproducibility.
