• Title of article

    A family of macrocyclic antibiotics with a mixed peptide–peptoid (beta)-hairpin backbone conformation

  • Author/Authors

    Robinson، John A. نويسنده , , Shankaramma، Sasalu C. نويسنده , , Moehle، Kerstin نويسنده , , James، Sonya نويسنده , , Vrijbloed، Jan W. نويسنده , , Obrecht، Daniel نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    -1841
  • From page
    1842
  • To page
    0
  • Abstract
    Macrocyclic peptidomimetics having a mixed peptide–peptoid backbone have been synthesized and shown to possess antibiotic activity against Gram-positive and -negative bacteria with a low hemolytic activity against human erythrocytes; one is shown to adopt a regular (beta)-hairpin conformation by NMR in aqueous solution.
  • Keywords
    inhibition of S(IV) autoxidation , atmospheric VOC , isoprene oxidation , Sulphur dioxide , isoprene
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Serial Year
    2003
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Record number

    70646