Title of article
Lipase-catalyzed domino kinetic resolution of (alpha)-hydroxynitrones/intramolecular 1,3-dipolar cycloaddition: a concise asymmetric total synthesis of (–)-rosmarinecine
Author/Authors
Kita، Yasuyuki نويسنده , , Akai، Shuji نويسنده , , Tanimoto، Kouichi نويسنده , , Kanao، Yukiko نويسنده , , Omura، Sohei نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2368
From page
2369
To page
0
Abstract
The title domino reactions were developed to directly provide tetrahydrofuro[3,4-c]isoxazole derivatives (5 and 9) in (greater than)90% ee from racemic (alpha)-hydroxynitrones (2 and 6), which were used in the concise asymmetric total synthesis of (–)-rosmarinecine 10.
Keywords
Oxidation , Fenton-like , H2O2 , Carbon-Fe catalysts , Orange II
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Serial Year
2005
Journal title
CHEMICAL COMMUNICATIONS - LETCHWORTH
Record number
70870
Link To Document