Author/Authors :
Sreedevi، Meesaraganda نويسنده Sri Krishnadevaraya Univerisity, Anantapur, Andhra Pradesh, India. , , Prasad، Aluru Raghavendra Guru Prasad نويسنده ICFAI Foundation for Higher Education, Hyderabad, Andhra Pradesh, India. , , Spoorthy، Yadati Narasimha نويسنده Sri Krishnadevaraya University, Anantapur, A.P., India. , , Ravindranath، Lakshmana Rao Krishna Rao نويسنده ,
Abstract :
Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity.
