Effects of Lindane Exposure on Rainbow-Trout (Oncorhynchus mykiss) Immunity : II. In Vitro Restoration of Antibody-Secreting Cells and Lymphocyte Proliferation Activity by Nitrogranulogen after in Vivo Immunosuppression Due to Lindane

A dose-dependent immunomodulatory effect of Nitrogranulogen (NGG) was observed in vitro on antibody-secreting cells and lymphocyte proliferation in rainbow trout. Because different doses of lindane (10, 50 and 100 mg/kg, injected intraperitoneally) had a depressing effect on the same immune functions, the authors restored them using NGG in vitro.