Author/Authors :
Junya Nagayama، نويسنده , , Ken Okamura، نويسنده , , TAKAO IIDA ، نويسنده , , Hironori Hirakawa، نويسنده , , Takahiko Matsueda، نويسنده , , Hiroshi Tsuji، نويسنده , , Mayumi Hasegawa، نويسنده , , Kayo Sato، نويسنده , , Using-Yi Ma، نويسنده , , Takashi Yanagawa، نويسنده , , Hisaji Igarashi، نويسنده , , Junichiro Fukushige، نويسنده , , Tadayoshi Watanabe، نويسنده ,
Abstract :
Effects of postnatal exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and coplanar polychlorinated biphenyls (Co-PCBs) on thyroid hormone status were studied in the peripheral blood of 36 breast-fed Japanese infants. Estimated total intakes of these chemicals in toxic equivalent quantity (TEQ) converted into 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) from the breast milk significantly and negatively correlated with the levels of triiodothyronine (T3) and thyroxme (T4) in the blood of breast-fed babies. Therefore, exposure to background levels of the highly toxic organochlorine chemicals through the breast milk may cause some effects on thyroid hormone status in Japanese infants.
