β -cyclodextrin(β -CD) influence on the biotoxicities of substituted benzene compounds and pesticide intermediates

The acute toxicities of 19 substituted benzene compounds and intermediates of pesticides to Photobacterium phosphoreum in β -CD aqueous solution (5 g/L) were studied and compared with those in water through luminescent bacteria toxicity test, and 15min-EC50 values were obtained. The presence of β -CD significantly reduce biotoxicities of the low-polarity compounds, while for the higher-polarity compounds, such effect was slight. The differences of biotoxicities were correlated with Log10Kow (octanol / water partition coefficients). A significant linear relationship was obtained with some abnormal data picked out. Some explanations concerning molecular structure of chemicals as well asβ -CD were given for the relationship.