Title of article :
Prediction of the fish acute toxicity from heterogeneous data coming from notification files
Author/Authors :
J. C. Faucon، نويسنده , , R. Bureau، نويسنده , , J. Faisant، نويسنده , , F. Briens، نويسنده , , S. Rault، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Pages :
16
From page :
3261
To page :
3276
Abstract :
Four descriptors (Molecular weight, log(Pow), hardness and free energy of solvation) were selected to predict, on a training set of heterogeneous chemical compounds, the fish acute toxicity. The data were extracted from 523 notification files of new chemicals stored at the French Department of the Environment. The selection of the descriptors was carried out by using a statistical technique coupling OLS regression and genetic algorithm. The limits of validity for the final equation are discussed by comparing the actual and predicted activities on several compounds.
Journal title :
Chemosphere
Serial Year :
1999
Journal title :
Chemosphere
Record number :
724228
Link To Document :
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