Form and selection of covariance adjusted estimators in repeated measures models

The GMANOVA model is considered when one characteristic is measured at q time points. The covariance adjusted estimator is the OLS estimator adjusted using analysis of covariance. The covariates are obtained from the space vertical to that derived from the design matrix. Its form is obtained as a GLS estimator using a weight matrix of reduced rank unless all available covariates are used. The choice of the appropriate covariate combination is made by introducing a method based on cross validation (CV). A comparison is made with two other methods that appeared in statistical literature using simulation.