Author/Authors :
Wu، Tao نويسنده , , Li، Ang نويسنده , , Miller، Eric L. نويسنده , , Kilmer، Misha E. نويسنده , , Brukilacchio، Thomas J. نويسنده , , Chaves، Tina نويسنده , , Stott، Jonathan نويسنده , , Zhang، Quan نويسنده , , Chorlton، MaryAnn نويسنده , , Moore، Richard H. نويسنده , , Kopans، Daniel B. نويسنده , , Boas، David A. نويسنده ,
Abstract :
We introduce a modified Tikhonov regularization method to include three-dimensional x-ray mammography as a prior in the diffuse optical tomography reconstruction. With simulations we show that the optical image reconstruction resolution and contrast are improved by implementing this x-ray-guided spatial constraint. We suggest an approach to find the optimal regularization parameters. The presented preliminary clinical result indicates the utility of the method.
Keywords :
optimal moments , Edgeworth expansion , U-statistics , nonlattice condition