Title of article :
The SMM model as a boundary value problem using the discrete diffusion equation
Author/Authors :
Joel Campbell، نويسنده ,
Issue Information :
دوماهنامه با شماره پیاپی سال 2007
Pages :
8
From page :
539
To page :
546
Abstract :
A generalized single-step stepwise mutation model (SMM) is developed that takes into account an arbitrary initial state to a certain partial difference equation. This is solved in both the approximate continuum limit and the more exact discrete form. A time evolution model is developed for Y DNA or mtDNA that takes into account the reflective boundary modeling minimum microsatellite length and the original difference equation. A comparison is made between the more widely known continuum Gaussian model and a discrete model, which is based on modified Bessel functions of the first kind. A correction is made to the SMM model for the probability that two individuals are related that takes into account a reflecting boundary modeling minimum microsatellite length. This method is generalized to take into account the general n-step model and exact solutions are found. A new model is proposed for the step distribution
Keywords :
Discrete diffusion , SMM , stepwise mutation , Infinite alleles , Bessel , microsatellite , n-step
Journal title :
Theoretical Population Biology
Serial Year :
2007
Journal title :
Theoretical Population Biology
Record number :
774034
Link To Document :
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