• Title of article

    Can one learn history from the allelic spectrum?

  • Author/Authors

    Simon Myers، نويسنده , , Charles Fefferman، نويسنده , , Nick Patterson، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2008
  • Pages
    7
  • From page
    342
  • To page
    348
  • Abstract
    It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfect information concerning the spectrum allows precise recovery of the history, and with an explicit example show that the answer is in the negative. This implies some limitations on how informative allelic spectra can be.
  • Keywords
    Diffusions , Allelic spectrum , Kimura
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2008
  • Journal title
    Theoretical Population Biology
  • Record number

    774067