Title of article
Can one learn history from the allelic spectrum?
Author/Authors
Simon Myers، نويسنده , , Charles Fefferman، نويسنده , , Nick Patterson، نويسنده ,
Issue Information
دوماهنامه با شماره پیاپی سال 2008
Pages
7
From page
342
To page
348
Abstract
It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfect information concerning the spectrum allows precise recovery of the history, and with an explicit example show that the answer is in the negative. This implies some limitations on how informative allelic spectra can be.
Keywords
Diffusions , Allelic spectrum , Kimura
Journal title
Theoretical Population Biology
Serial Year
2008
Journal title
Theoretical Population Biology
Record number
774067
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