Title of article
Taenia solium dUTPase: A potential target for anti-human cysticercosis
Author/Authors
Yadong Zheng، نويسنده , , Xuenong Luo، نويسنده , , Zhenyong Liu، نويسنده , , Zhizhong Jing، نويسنده , , Wanzhong Jia، نويسنده , , Xuepeng Cai، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
266
To page
270
Abstract
dUTPase plays an essential role in pyrimidine metabolism in many organisms. In this study we report the dUTPase-encoding gene (Tdut) from Taenia solium oncospheres and larvae. Alignment reveals that the putative protein contains five conserved motifs that are often found in many characterized dUTPases. The deduced amino acid sequence has only 65.2% identity with human dUTPases. This low identity encourages its use for the design of new drugs against cysticercosis.
Keywords
Taenia solium , dUTPase , Anti-cysticercosis drug
Journal title
Acta Tropica
Serial Year
2007
Journal title
Acta Tropica
Record number
778480
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