Title of article :
Immunity against prions?
Author/Authors :
Frank L. Heppner، نويسنده , , Isabelle Arrighi، نويسنده , , Ulrich Kalinke، نويسنده , , Adriano Aguzzi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Pages :
3
From page :
477
To page :
479
Abstract :
Several recent reports indicate that antibodies directed against the cellular form of the prion protein, PrPC, might eliminate the transmissible agent of spongiform encephalopathies (the prion) from scrapie-infected cells in vitro, and that a humoral immune response could prevent scrapie pathogenesis in vivo. These findings suggest that immunotherapeutical intervention against prion diseases is not unattainable. Will vaccines and post-exposure strategies based on antibodies ever prove useful against scrapie, bovine spongiform encephalopathy (BSE), or Creutzfeldt–Jakob disease?
Journal title :
Trends in Molecular Medicine
Serial Year :
2001
Journal title :
Trends in Molecular Medicine
Record number :
783821
Link To Document :
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