Author/Authors :
Alongkorn Amonsin، نويسنده , , Salin Chutinimitkul، نويسنده , , Nuananong Pariyothorn، نويسنده , , Thaweesak Songserm، نويسنده , , Sudarat Damrongwantanapokin، نويسنده , , Suphasawatt Puranaveja، نويسنده , , Rungroj Jam-on، نويسنده , , Namdee Sae-Heng، نويسنده , , Sunchai Payungporn، نويسنده , , Apiradee Theamboonlers، نويسنده , , Arunee Chaisingh، نويسنده , , Rachod Tantilertcharoen، نويسنده , , Sanipa Suradhat، نويسنده , , Roongroje Thanawongnuwech، نويسنده , , Yong Poovorawan، نويسنده ,
Abstract :
Three major outbreaks of avian influenza (AI) occurred in Thailand. During the third episode in October 2005, we have isolated H5N1 viruses from one human case and three poultry cases. The whole genomes of AI viruses from human, chickens and quail from the outbreaks were characterized. Sequence analysis of eight gene segments revealed that the 2005 H5N1 viruses isolated in October 2005 were closely related to those recovered from chicken, tiger(s) and human(s) in January and July 2004. In addition, the genetic changes of the AI isolates at the HA cleavage site have been observed.
Keywords :
H5N1 , Influenza A virus , characterization , Thailand
