Author/Authors :
Elisabet Wits?، نويسنده , , Gustavo Palacios، نويسنده , , Kjersti S. R?nningen، نويسنده , , Ondrej Cinek، نويسنده , , Diana Janowitz، نويسنده , , Marian Rewers، نويسنده , , Bjorn Grinde، نويسنده , , W. Ian Lipkin، نويسنده ,
Abstract :
Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype C1. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5′UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence.
