Title of article
N-(carbobenzyloxy)isatin: A slow binding α-keto lactam inhibitor of α-chymotrypsin
Author/Authors
Ramaswamy A. Iyer، نويسنده , , Patrick E. Hanna، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
89
To page
92
Abstract
The N-carbobenzyloxy derivative of 2,3-dioxindole (N-Cbz-isatin) (1) has been synthesized and shown to be a slow binding inhibitor of chymotrypsin. Compound 1 does not inhibit porcine pancreatic elastase. The N-tert-butoxycarbonyl derivative of 2,3-dioxindole (2) is a weak inhibitor of chymotrypsin and does not inhibit porcine pancreatic elastase.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787286
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