Non-peptide oxytocin antagonists: identification and synthesis of a potent camphor aminosuccinimide
Author/Authors :
Doug W. Hobbs، نويسنده , , Norman P. Gould، نويسنده , , James B. Hoffman، نويسنده , , Bradley V. Clineschmidt، نويسنده , , Douglas J. Pettibone، نويسنده , , Daniel F. Veber، نويسنده , , Roger M. Freidinger، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Pages :
4
From page :
119
To page :
122
Abstract :
The structure activity relationships of a series of non-peptide oxytocin antagonists containing a camphor aminosuccinimide as a key structural element were investigated. A potent and selective analog was identified and prepared in diastereomerically pure form starting from aspartic acid.
