Molecular modeling studies on 11β-aminoethoxyphenyl and 7α-aminoethoxyphenyl estradiols. evidence suggesting a common hydrophobic pocket in estrogen receptor

Molecular modeling studies were performed on 11β and 7α-aminoethoxyphenyl estradiols to determine whether these compounds may interact with the same receptor subsite. Energy minimization and molecular dynamics studies lend support to this hypothesis.