Title of article
FPL 64176: The effect of the chain length separating the two aryl groups on calcium agonist activity
Author/Authors
John M. Kane، نويسنده , , Christopher R. Dalton، نويسنده , , Nelson L. Velayo، نويسنده , , David Rampe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
873
To page
876
Abstract
Analogs of the L-type calcium channel agonist FPL 64176 (5) were prepared in which the chain length separating the two aryl moieties was varied between zero and four. FPL 64176 (5) and phenethyl derivative 19 were the most potent compounds tested, displaying EC50 values for enhancing calcium influx into GH3 cells of 1−2×10−7 M.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787434
Link To Document