• Title of article

    Molecular design of novel PGI2 agonists without PG skeleton. III

  • Author/Authors

    Nobuyuki Hamanaka، نويسنده , , Kanji Takahashi، نويسنده , , Yuuki Nagao، نويسنده , , Kazuhiko Torisu، نويسنده , , Hidekado Tokumoto، نويسنده , , Kigen Kondo، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    1077
  • To page
    1082
  • Abstract
    Several ether, oxime, and amide derivatives related to 1 and 3 were synthesized and tested as PGI2 agonists. The results reveal the importance of the orientation between carboxylic acid and terminal diphenyl groups in order to obtain high affinity interaction with PGI2 receptors.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787472

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=787472