• Title of article

    Thiourea analogues of resiniferatoxin as ligands for the vanilloid receptor

  • Author/Authors

    Jeewoo Lee، نويسنده , , Geza Acs، نويسنده , , Peter M. Blumberg، نويسنده , , Victor E. Marquez، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    4
  • From page
    1331
  • To page
    1334
  • Abstract
    A thiourea bridge was tested as a linker to replace the OC(O)CH2 ester group that connects resiniferonol-9,13,14-orthophenylacetate to the 3-methoxy-4-hydroxyphenyl moiety in resiniferatoxin (RTX). The resulting compounds showed lower affinity for the vanilloid receptor than did the parent RTX.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787519