Title of article
Enantioselective oxidation of 2-methyl-1-alkanols by alcohol oxidase from methylotrophic yeasts
Author/Authors
Dawn S. Clark، نويسنده , , Shimona Geresh، نويسنده , , Robert DiCosimo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
1383
To page
1388
Abstract
The oxidation of several racemic 2-methyl-1-alkanols by the alcohol oxidase from Candida boidinii, Hansenula sp., Pichia pastoris, and Torulopsis methanothermo afforded reaction mixtures enriched in (R)-2-methyl-1-alkanol at incomplete conversions. The alcohol oxidase from C. boidinii exhibited the highest enantioselectivity, with the greatest enantiomeric excess obtained for (R)-2-methyl-1-pentanol (90.6 % ee at 76 % conversion; E = 4.8).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787528
Link To Document