Title of article
A novel non nucleoside compound with high in vitro anti-HIV-1 activity. Absolute stereochemistry determination
Author/Authors
De la Fuente Jes?s A.، نويسنده , , Marug?n Juan J.، نويسنده , , Cross Sue S.، نويسنده , , Mateos Alfonso F.، نويسنده , , A. Garcia Santiago، نويسنده , , Menéndez Amador، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
1471
To page
1474
Abstract
Here we report a novel non-nucleoside compound, PM-92131(+), with in vitro anti-HIV-1 activity. This product was synthesized as a pure enantiomer via diastereomeric ester formation and selective crystallisation and its absolute stereochemistry was determined by X-ray diffraction analysis. Results from the activity assays suggest PM-92131(+) could be a promising new compound for further assessment as a potential anti-HIV-1 agent.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787543
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