3-Fluoro-2-(4-methylpiperazin-1-yl)-5,12-dihydro-5-oxobenzoxazolo[3,2-a]quinoline-6-carboxylic acid: Synthesis and In vitro cytotoxic activity

The title compound which shows a potent in vitro cytotoxic activity has been synthesized employing the tandem double ring closure reaction of N-acyl-N-(2′-hydroxyphenyl) anthranilic acid with acetic anhydride as a key step.