A case study of combinatorial libraries: Endothelin receptor antagonist hexapeptides
Author/Authors :
B. Neustadt، نويسنده , , A. Wu، نويسنده , , E. M. Smith، نويسنده , , T. Nechuta، نويسنده , , Amani A. Fawzi، نويسنده , , H. Zhang، نويسنده , , A. K. Ganguly، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Pages :
4
From page :
2041
To page :
2044
Abstract :
Combinatorial libraries were constructed based on a hexapeptide endothelin receptor antagonist. Iterative optimization efficiently identified the most active member of the library and allowed preparation of a more potent antagonist.
