Title of article :
Synthetic inhibitors of interleukin-6 II: 3,5-diaryl pyridines and meta-terphenyls
Author/Authors :
Jayaram R. Tagat، نويسنده , , Stuart W. McCombie، نويسنده , , Beverly E. Barton، نويسنده , , James Jackson، نويسنده , , Jennifer Shortall، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1995
Abstract :
An efficient synthesis of the title compounds using the Ni (II) catalysed coupling of various aryl magnesium bromides with di-halo pyridines and di-halo benzenes is reported. Among the several compounds tested, 1, 2, 12 and 17 showed good inhibitory activity against interleukin-6.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
