Title of article
Synthesis of FK506-Cyclosporin hybrid macrocycles
Author/Authors
Simon J. Teague، نويسنده , , Martin E. Cooper، نويسنده , , Michael J. Stocks، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
2341
To page
2346
Abstract
An attempt was made to synthesise calcineurin inhibitors using dual domain macrocyclic compounds that incorporated a FKBP12 binding domain together with a calcineurin recognition domain which had been designed by consideration of the relevant features of both FK506 and Cyclosporin A.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787706
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