Author/Authors :
Marina Gordaliza، نويسنده , , José M Miguel del Corral، نويسنده , , M Angeles Castro، نويسنده , , M Luisa L?pez-V?zquez، نويسنده , , Pablo A. Garc?a، نويسنده , , Arturo San Feliciano، نويسنده , , M Dolores Garc?a-Gr?valos، نويسنده ,
Abstract :
Several derivatives of podophyllotoxin, lacking the lactone moiety and with nitrogen substituents at C-7 or C-9, have been prepared. They have been evaluated for their cytotoxic activity in P-388, A-549, HT-29 and MEL-28 culture cells. Some of them show a highly selective cytotoxicity towards HT-29 human colon carcinoma.
