Title of article
Direct evidence for DNA intrastrand cross-linking by the nitrogen mustard mechlorethamine in synthetic oligonucleotides
Author/Authors
Stacia M. Rink، نويسنده , , Paul B. Hopkins، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
2845
To page
2850
Abstract
Direct evidence for DNA intrastrand cross-link formation by mechlorethamine (1) is reported. Following treatment with 1, duplex and single strand DNAs possessing two or more contiguous dG residues contained intrastrand cross-links, as revealed by the release of 2 following acid hydrolysis.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787796
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