Title of article
Anti HIV-1 activity of a hydrophilic cyclosporin derivative with improved binding affinity to cyclophilin A
Author/Authors
Christos Papageorgiou، نويسنده , , Jean-Jacques Sanglier، نويسنده , , René Traber، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
23
To page
26
Abstract
Due to its conformation, the hydrophilic compound [(D)MeSer-3, (4-OH)MeLeu-4] cyclosporin, 3, shows high affinity for cyclophilin A. This property, together with its lack of immunosuppression, confers 3 with very interesting anti HIV-1 activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787849
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