Title of article :
Potent inhibitors of neutral endopeptidase. 2-Biphenyl- methylglutaric acid amide derivatives
Author/Authors :
Hideyuki Kanno، نويسنده , , Ken Osanai، نويسنده , , Taketoshi Furugohri، نويسنده , , Yoshifumi Watanabe، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
A series of glutaric acid amide derivatives were synthesized and tested for NEP inhibitory activity. Compounds 14a, 14b, 16a and 22, with a biphenylmethyl group at P′1 position, showed potent inhibitory activity.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
